abstract：:Selecting a set of relevant markers to predict conversion from mild cognitive impairment (MCI) to Alzheimer's disease (AD) has become a challenging task given the wealth of regional pathologic information that can be extracted from multimodal imaging data. Here, we used regularized regression approaches with an elasti...

journal_title：NeuroImage. Clinical

authors： Teipel SJ,Kurth J,Krause B,Grothe MJ,Alzheimer's Disease Neuroimaging Initiative.

更新日期：2015-05-21 00:00:00

abstract：:DTI studies in multiple sclerosis (MS) reveal white matter (WM) injury that occurs with disease progression. In the present study we aimed to elucidate the relationship of microstructural WM damage in patients with varying periods of disease duration. DTI scans were acquired from 90 MS patients and 25 healthy controls...

journal_title：NeuroImage. Clinical

authors： Asaf A,Evan S,Anat A

更新日期：2015-04-30 00:00:00

abstract：BACKGROUND:Individuals with at-risk mental state for psychosis (ARMS) often suffer from depressive and anxiety symptoms, which are clinically similar to the negative symptomatology described for psychosis. Thus, many ARMS individuals are already being treated with antidepressant medication. OBJECTIVES:To investigate c...

journal_title：NeuroImage. Clinical

authors： Bernasconi R,Smieskova R,Schmidt A,Harrisberger F,Raschle NM,Lenz C,Walter A,Simon A,Riecher-Rössler A,Radue EW,Lang UE,Fusar-Poli P,Borgwardt SJ

更新日期：2015-04-29 00:00:00

abstract：:Post-stroke impairment is associated not only with structural lesions, but also with dysfunction in surviving perilesional tissue. Previous studies using equivalent current dipole source localization of MEG/EEG signals have demonstrated a preponderance of slow-wave activity localized to perilesional areas. Recent stud...

journal_title：NeuroImage. Clinical

authors： Chu RK,Braun AR,Meltzer JA

更新日期：2015-04-08 00:00:00

abstract：:Independent studies on major depressive disorder (MDD) and hypertension, suggest overlapping abnormalities in brain regions associated with emotional and autonomic processing. However, the unique and interactive effects of MDD and hypertension have never been studied in a single sample. Brain volume in these areas may...

journal_title：NeuroImage. Clinical

authors： Meurs M,Groenewold NA,Roest AM,van der Wee NJ,Veltman DJ,van Tol MJ,de Jonge P

更新日期：2015-03-28 00:00:00

abstract：BACKGROUND:Diffusion imaging tractography is increasingly used to trace critical fiber tracts in brain tumor patients to reduce the risk of post-operative neurological deficit. However, the effects of peritumoral edema pose a challenge to conventional tractography using the standard diffusion tensor model. The aim of t...

journal_title：NeuroImage. Clinical

authors： Chen Z,Tie Y,Olubiyi O,Rigolo L,Mehrtash A,Norton I,Pasternak O,Rathi Y,Golby AJ,O'Donnell LJ

更新日期：2015-03-20 00:00:00

abstract：:Limb weakness in amyotrophic lateral sclerosis (ALS) is typically asymmetric. Previous studies have identified an effect of limb dominance on onset and spread of weakness, however relative atrophy of dominant and non-dominant brain regions has not been investigated. Our objective was to use voxel-based morphometry (VB...

journal_title：NeuroImage. Clinical

authors： Devine MS,Pannek K,Coulthard A,McCombe PA,Rose SE,Henderson RD

更新日期：2015-03-14 00:00:00

abstract：BACKGROUND:There is little known about cardiorespiratory fitness and its association with volumes of the thalamus, hippocampus, and basal ganglia in multiple sclerosis (MS). Such inquiry is important for identifying a possible behavioral approach (e.g., aerobic exercise training) that might change volumes of deep gray ...

journal_title：NeuroImage. Clinical

authors： Motl RW,Pilutti LA,Hubbard EA,Wetter NC,Sosnoff JJ,Sutton BP

更新日期：2015-02-26 00:00:00

abstract：:Verbal information is better retained when it is self-generated rather than when it is received passively. The application of self-generation procedures has been found to improve memory in healthy elderly and in individuals with impaired cognition. Overall, the available studies support the notion that active particip...

journal_title：NeuroImage. Clinical

authors： Vannest J,Maloney T,Kay B,Siegel M,Allendorfer JB,Banks C,Altaye M,Szaflarski JP

更新日期：2015-02-20 00:00:00

abstract：:Cerebral small vessel disease, including white matter hyperintensities (WMH) and lacunes of presumed vascular origin, is common in elderly people and is related to cognitive impairment and dementia. One possible mechanism could be the disruption of white matter tracts (both within WMH and normal-appearing white matter...

journal_title：NeuroImage. Clinical

authors： Tuladhar AM,van Norden AG,de Laat KF,Zwiers MP,van Dijk EJ,Norris DG,de Leeuw FE

更新日期：2015-02-16 00:00:00

abstract：:Patients with congenital heart disease (CHD) are at risk for neurocognitive impairments. Little is known about the impact of CHD on the organization of large-scale brain networks. We applied graph analysis techniques to diffusion tensor imaging (DTI) data obtained from 49 adolescents with dextro-transposition of the g...

journal_title：NeuroImage. Clinical

authors： Panigrahy A,Schmithorst VJ,Wisnowski JL,Watson CG,Bellinger DC,Newburger JW,Rivkin MJ

更新日期：2015-01-27 00:00:00

abstract：:The present study investigated the pattern of longitudinal changes in cognition and anatomy in three variants of primary progressive aphasia (PPA). Eight patients with the non-fluent variant of PPA (nfvPPA), 13 patients with the semantic variant (svPPA), seven patients with the logopenic variant (lvPPA), and 29 age-ma...

journal_title：NeuroImage. Clinical

authors： Brambati SM,Amici S,Racine CA,Neuhaus J,Miller Z,Ogar J,Dronkers N,Miller BL,Rosen H,Gorno-Tempini ML

更新日期：2015-01-22 00:00:00

abstract：:In the post combination antiretroviral therapy (cART) era, the prevalence of mild forms of HIV-associated neurocognitive disorders (HAND) in individuals with HIV-infection remains high. There is a pressing need to find biomarkers that can aid clinical assessment of HAND, especially in those with mild or no neurocognit...

journal_title：NeuroImage. Clinical

authors： Liu C,Wang C,Leclair M,Young M,Jiang X

更新日期：2014-12-13 00:00:00

abstract：:[(18)F]FDG-PET imaging has been recognized as a crucial diagnostic marker in Mild Cognitive Impairment (MCI), supporting the presence or the exclusion of Alzheimer's Disease (AD) pathology. A clinical heterogeneity, however, underlies MCI definition. In this study, we aimed to evaluate the predictive role of single-su...

journal_title：NeuroImage. Clinical

authors： Cerami C,Della Rosa PA,Magnani G,Santangelo R,Marcone A,Cappa SF,Perani D

更新日期：2014-12-05 00:00:00

abstract：:In order to analyze functional connectivity in untreated and treated patients with schizophrenia, resting-state fMRI data were obtained for whole-brain functional connectivity analysis from 22 first-episode neuroleptic-naïve schizophrenia (NNS), 61 first-episode neuroleptic-treated schizophrenia (NTS) patients, and 60...

journal_title：NeuroImage. Clinical

authors： Pu W,Rolls ET,Guo S,Liu H,Yu Y,Xue Z,Feng J,Liu Z

更新日期：2014-10-16 00:00:00

abstract：:Autism Spectrum Disorder (ASD) is characterized by impairments in language and social-emotional cognition. Yet, findings of emotion recognition from affective prosody in individuals with ASD are inconsistent. This study investigated emotion recognition and neural processing of affective prosody in high-functioning adu...

journal_title：NeuroImage. Clinical

authors： Gebauer L,Skewes J,Hørlyck L,Vuust P

更新日期：2014-10-05 00:00:00

abstract：:Muscle sympathetic nerve activity (MSNA) is greatly elevated in patients with obstructive sleep apnoea (OSA) during daytime wakefulness, leading to hypertension, but the underlying mechanisms are poorly understood. By recording MSNA concurrently with functional Magnetic Resonance Imaging (fMRI) of the brain we aimed t...

journal_title：NeuroImage. Clinical

authors： Fatouleh RH,Hammam E,Lundblad LC,Macey PM,McKenzie DK,Henderson LA,Macefield VG

更新日期：2014-08-27 00:00:00

abstract：BACKGROUND:In Friedreich's ataxia (FA) the genetically decreased expression of the mitochondrial protein frataxin leads to disturbance of the mitochondrial iron metabolism. Within the cerebellum the dentate nuclei (DN) are primarily affected. Histopathological studies show atrophy and accumulation of mitochondrial iron...

journal_title：NeuroImage. Clinical

authors： Solbach K,Kraff O,Minnerop M,Beck A,Schöls L,Gizewski ER,Ladd ME,Timmann D

更新日期：2014-08-23 00:00:00

abstract：:Multiple sclerosis (MS) is characterized by the formation of demyelinating lesions in the white matter (WM). However, the timecourse of the evolution of healthy white matter into fully demyelinated lesions in MS is not well understood. We use a recently proposed technique to examine magnetization transfer ratio (MTR) ...

journal_title：NeuroImage. Clinical

authors： Brown RA,Narayanan S,Arnold DL

更新日期：2014-08-15 00:00:00

abstract：:Alterations in cortical development and impaired neurodevelopmental outcomes have been described following very preterm (VPT) birth in childhood and adolescence, but only a few studies to date have investigated grey matter (GM) and white matter (WM) maturation in VPT samples in early adult life. Using voxel-based morp...

journal_title：NeuroImage. Clinical

authors： Nosarti C,Nam KW,Walshe M,Murray RM,Cuddy M,Rifkin L,Allin MP

更新日期：2014-08-13 00:00:00

abstract：:Noninvasive markers of brain function could yield biomarkers in many neurological disorders. Disease models constrained by coordinate-based meta-analysis are likely to increase this yield. Here, we evaluate a thalamic model of temporal lobe epilepsy that we proposed in a coordinate-based meta-analysis and extended in ...

journal_title：NeuroImage. Clinical

authors： Barron DS,Fox PT,Pardoe H,Lancaster J,Price LR,Blackmon K,Berry K,Cavazos JE,Kuzniecky R,Devinsky O,Thesen T

更新日期：2014-08-07 00:00:00

abstract：:Post-traumatic stress disorder (PTSD) is a leading cause of sustained impairment, distress, and poor quality of life in military personnel, veterans, and civilians. Indirect functional neuroimaging studies using PET or fMRI with fear-related stimuli support a PTSD neurocircuitry model that includes amygdala, hippocamp...

journal_title：NeuroImage. Clinical

authors： Huang MX,Yurgil KA,Robb A,Angeles A,Diwakar M,Risbrough VB,Nichols SL,McLay R,Theilmann RJ,Song T,Huang CW,Lee RR,Baker DG

更新日期：2014-08-07 00:00:00

abstract：:In Alzheimer's disease (AD), the hippocampus is an early site of tau pathology and neurodegeneration. Histological studies have shown that lesions are not uniformly distributed within the hippocampus. Moreover, alterations of different hippocampal layers may reflect distinct pathological processes. 7 T MRI dramaticall...

journal_title：NeuroImage. Clinical

authors： Boutet C,Chupin M,Lehéricy S,Marrakchi-Kacem L,Epelbaum S,Poupon C,Wiggins C,Vignaud A,Hasboun D,Defontaines B,Hanon O,Dubois B,Sarazin M,Hertz-Pannier L,Colliot O

更新日期：2014-07-31 00:00:00

abstract：:Multi-modal magnetic resonance imaging (MRI) that included high resolution structural imaging, diffusion tensor imaging (DTI), magnetization transfer ratio (MTR) imaging, and magnetic resonance spectroscopic imaging (MRSI) were performed in mild traumatic brain injury (mTBI) patients with negative computed tomographic...

journal_title：NeuroImage. Clinical

authors： Narayana PA,Yu X,Hasan KM,Wilde EA,Levin HS,Hunter JV,Miller ER,Patel VK,Robertson CS,McCarthy JJ

更新日期：2014-07-24 00:00:00

abstract：:The symptoms witnessed in unexplained death in epilepsy (SUDEP) suggest a breakdown of central autonomic control. Since the brainstem plays a crucial role in autonomic control, the objectives of this study were 1. To investigate if temporal lobe epilepsy (TLE) is associated with brainstem atrophy and to characterize i...

journal_title：NeuroImage. Clinical

authors： Mueller SG,Bateman LM,Laxer KD

更新日期：2014-07-09 00:00:00

abstract：:Electrical source imaging (ESI) aims at reconstructing the electrical brain activity from scalp EEG. When applied to interictal epileptiform discharges (IEDs), this technique is of great use for identifying the irritative zone in focal epilepsies. Inaccuracies in the modeling of electro-magnetic field propagation in t...

journal_title：NeuroImage. Clinical

authors： Birot G,Spinelli L,Vulliémoz S,Mégevand P,Brunet D,Seeck M,Michel CM

更新日期：2014-06-16 00:00:00

abstract：BACKGROUND:Violence that leads to homicide results in an extreme financial and emotional burden on society. Juveniles who commit homicide are often tried in adult court and typically spend the majority of their lives in prison. Despite the enormous costs associated with homicidal behavior, there have been no serious ne...

journal_title：NeuroImage. Clinical

authors： Cope LM,Ermer E,Gaudet LM,Steele VR,Eckhardt AL,Arbabshirani MR,Caldwell MF,Calhoun VD,Kiehl KA

更新日期：2014-05-10 00:00:00

abstract：:Multivariate classification is used in neuroimaging studies to infer brain activation or in medical applications to infer diagnosis. Their results are often assessed through either a binomial or a permutation test. Here, we simulated classification results of generated random data to assess the influence of the cross-...

journal_title：NeuroImage. Clinical

authors： Noirhomme Q,Lesenfants D,Gomez F,Soddu A,Schrouff J,Garraux G,Luxen A,Phillips C,Laureys S

更新日期：2014-04-13 00:00:00

abstract：:Anxiety disorders have been linked to a hyperactivated cortico-amygdalar circuitry. Recent findings highlight the amygdala's role in mediating elevated anxiety in obsessive-compulsive disorder (OCD). However, modulation of amygdala hyperactivation by attentional distraction - an effective emotion regulation strategy i...

journal_title：NeuroImage. Clinical

authors： Simon D,Adler N,Kaufmann C,Kathmann N

更新日期：2014-03-26 00:00:00

abstract：:Autism spectrum disorder is associated with an altered early brain development. However, the specific cortical structure abnormalities underlying this disorder remain largely unknown. Nonetheless, atypical cortical folding provides lingering evidence of early disruptions in neurodevelopmental processes and identifying...

journal_title：NeuroImage. Clinical

authors： Auzias G,Viellard M,Takerkart S,Villeneuve N,Poinso F,Fonséca DD,Girard N,Deruelle C

更新日期：2014-03-25 00:00:00

abstract：:Obstructive sleep apnea (OSA) is accompanied by cognitive, motor, autonomic, learning, and affective abnormalities. The putamen serves several of these functions, especially motor and autonomic behaviors, but whether global and specific sub-regions of that structure are damaged is unclear. We assessed global and regio...

journal_title：NeuroImage. Clinical

authors： Kumar R,Farahvar S,Ogren JA,Macey PM,Thompson PM,Woo MA,Yan-Go FL,Harper RM

更新日期：2014-01-31 00:00:00

abstract：BACKGROUND:Chronic cyanosis in adults with congenital heart disease (CHD) may cause structural brain changes that could contribute to impaired neurological functioning. The extent of these changes has not been adequately characterized. HYPOTHESIS:We hypothesized that adults with cyanotic CHD would have widespread chan...

journal_title：NeuroImage. Clinical

authors： Cordina R,Grieve S,Barnett M,Lagopoulos J,Malitz N,Celermajer DS

更新日期：2014-01-04 00:00:00

abstract：:Gilles de la Tourette syndrome (GTS) is a common developmental neuropsychiatric disorder characterized by tics and frequent psychiatric comorbidities, often causing significant disability. Tic generation has been linked to disturbed networks of brain areas involved in planning, controlling and execution of actions, pa...

journal_title：NeuroImage. Clinical

authors： Cheng B,Braass H,Ganos C,Treszl A,Biermann-Ruben K,Hummel FC,Müller-Vahl K,Schnitzler A,Gerloff C,Münchau A,Thomalla G

更新日期：2013-12-07 00:00:00

abstract：:There is increasing interest in developing a reliable, affordable and accessible disease biomarker of Parkinson's disease (PD) to facilitate disease modifying PD-trials. Imaging biomarkers using magnetic resonance imaging (MRI) and diffusion tensor imaging (DTI) can describe parameters such as fractional anisotropy (F...

journal_title：NeuroImage. Clinical

authors： Schwarz ST,Abaei M,Gontu V,Morgan PS,Bajaj N,Auer DP

更新日期：2013-10-14 00:00:00

abstract：:Establishing a reliable correspondence between lesioned brains and a template is challenging using current normalization techniques. The optimum procedure has not been conclusively established, and a critical dichotomy is whether to use input data sets which contain skull signal, or whether skull signal should be remo...

journal_title：NeuroImage. Clinical

authors： Fischmeister FP,Höllinger I,Klinger N,Geissler A,Wurnig MC,Matt E,Rath J,Robinson SD,Trattnig S,Beisteiner R

更新日期：2013-09-30 00:00:00

abstract：:This paper examines morphometry of MRI biomarkers derived from the network of temporal lobe structures including the amygdala, entorhinal cortex and hippocampus in subjects with preclinical Alzheimer's disease (AD). Based on template-centered population analysis, it is demonstrated that the structural markers of the a...

journal_title：NeuroImage. Clinical

authors： Miller MI,Younes L,Ratnanather JT,Brown T,Trinh H,Postell E,Lee DS,Wang MC,Mori S,O'Brien R,Albert M,BIOCARD Research Team.

更新日期：2013-09-16 00:00:00

abstract：:Although brain plasticity in the form of gray matter increases and decreases has been observed in chronic pain, factors determining the patterns of directionality are largely unknown. Here we tested the hypothesis that fibromyalgia interacts with age to produce distinct patterns of gray matter differences, specificall...

journal_title：NeuroImage. Clinical

authors： Ceko M,Bushnell MC,Fitzcharles MA,Schweinhardt P

更新日期：2013-09-06 00:00:00

abstract：:Fibromyalgia syndrome is a chronic pain disorder characterised by widespread pain and tenderness in muscles and deep tissues. Current theories regarding the pathophysiological origins of fibromyalgia syndrome point towards central sensitisation and a decreased capacity of descending nociceptive controls. Morphological...

journal_title：NeuroImage. Clinical

authors： Fallon N,Alghamdi J,Chiu Y,Sluming V,Nurmikko T,Stancak A

更新日期：2013-08-09 00:00:00

abstract：:Atypical visual perception in people with autism spectrum disorders (ASD) is hypothesized to stem from an imbalance in excitatory and inhibitory processes in the brain. We used neuronal oscillations in the gamma frequency range (30-90 Hz), which emerge from a balanced interaction of excitation and inhibition in the br...

journal_title：NeuroImage. Clinical

authors： Snijders TM,Milivojevic B,Kemner C

更新日期：2013-07-02 00:00:00

abstract：:Slowed information processing speed is commonly reported in persons with multiple sclerosis (MS), and is typically investigated using clinical neuropsychological tests, which provide sensitive indices of mean-level information processing speed. However, recent studies have demonstrated that within-person variability o...

journal_title：NeuroImage. Clinical

authors： Mazerolle EL,Wojtowicz MA,Omisade A,Fisk JD

更新日期：2013-06-28 00:00:00